Antofagasta Region Holidays
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Your Antofagasta Region Holiday
Answer the call of adventure with a tailor-made holiday package to Antofagasta Region. Wherever your travels take you and whatever you plan to do, prepare to experience a destination that'll make you truly feel alive. The easiest way to organise your trip to Antofagasta Region is to begin with its most popular cities, which include San Pedro de Atacama, Antofagasta and Historical District. Expedia has flights, hotels, car rentals and more to help you organise your very own customised Antofagasta Region holiday today.
Top destinations in Antofagasta Region
San Pedro de Atacama
Calama
Antofagasta Region Essential Information
Language | Spanish |
|---|---|
Currency | Chilean pesos |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Closest Airport | Calama Airport (CJC) |
Population | 309,800 |
Top Sights | Valley of the Moon, Piedra del Coyote Overlook and Arco Iris Valley |
Our pick of the best Antofagasta Region Hotel Deals
Diego de Almagro San Pedro de Atacama
Toconao 460 San Pedro de Atacama Antofagasta
Fully refundableReserve now, pay when you stay
AU$160
20 Aug - 21 Aug
8.2/10 Very good! (401 reviews)
"Staff very helpful and friendly, although no English. Happy to converse using translation tools. Swimming pool was closed due to it being winter, which I didn’t reslise when I booked. A couple of times there was no water, no electricity and no wifi, but staff worked to resolve the issue. Breakfast ..."
Reviewed on 18 July 2026
Hotel La Casa de Don Tomas
Calle Tocopilla Sitio 18 San Pedro de Atacama
Fully refundableReserve now, pay when you stay
AU$296
20 Aug - 21 Aug
Geotel Calama
Cobija 2273 Calama Antofagasta
Fully refundableReserve now, pay when you stay
AU$103
21 Aug - 22 Aug
8.8/10 Excellent! (235 reviews)
"Reservation for 1 Double 2 bedrooms apartment. Changed for 2 singles. Heather non-working. Breakfast to.go offered but Non ready when leaving."
Reviewed on 29 July 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
How much does an Antofagasta Region holiday package cost?
From as low as . Yes, you read that right. Our Antofagasta Region packages are the best way to stretch your budget. Combine your hotels, flights and car rentals and discover this lively destination.
How do I get a cheap travel package to Antofagasta Region?
Our Antofagasta Region holiday packages promise plenty of savings for the savvy traveller. For the best deals, simply bundle your hotel, flights and activities into an affordable package. But impressive bargains are only the start of your next unforgettable adventure. Book with Expedia and you'll have more than 550 airlines and 1 000 000 properties throughout the world to pick from. Whatever your budget, there's a package that's perfect for you.
What are the top hotels in Antofagasta Region?
Have a look at ibis Antofagasta and NH Antofagasta. They're the first choice for lots of travellers to Antofagasta. If San Pedro de Atacama is on your travel itinerary, Park Hotel Calama and Noi Casa Atacama are cosy options.
How far in advance should I book my Antofagasta Region holiday?
It can be tricky to know when is the ideal time to book your trip to Antofagasta Region. But typically the earlier you book, the better the prices. Sometimes, you can reserve your flights and hotels up to a year before your departure date. If you're considering a last-minute getaway, no need to stress! There are fabulous deals featured on Expedia every single day.
What does an Expedia Antofagasta Region travel package include?
From hotels and airfares to rental cars, Expedia can help you shape an Antofagasta Region package that's perfect for you. Holidaying for a week or two? Consider a rental car, hotel and flight bundle. If you're taking a short break, a flight and hotel deal could be more your style. Activities can also be added once you've made your booking. Our holiday packages make it simple to save and plan.
What should I know before booking an Antofagasta Region travel package?
Tailor deals to suit your budget with an Expedia package. Airfares, hotels, rental cars — we're a one-stop shop for all of them. You'll save precious dollars just for bundling your bookings. Whether you're embarking on a skiing adventure or drinking cocktails on a beach, your perfect getaway is just clicks away.
Can I choose my airline with an Antofagasta Region Expedia holiday package?
Expedia has access to more than 550 airline partners worldwide, so you sure can! Simply select your preferred carrier and put together the perfect Antofagasta Region trip.
If I'm not able to travel, can I cancel my Antofagasta Region holiday package?
Whether it's your flight or hotel, you can cancel and rebook it. Locked in your Antofagasta Region holiday package in the last 24 hours? You may be able to make changes at no cost. For bookings older than that, you may be charged a fee by your hotel, airline or car rental company. For further information, visit our Customer Service Portal. We'll help you every step of the way.
Stay near popular Antofagasta Region attractions
Valley of the Moon
9.2/10 (244 reviews)
Treat your eyes to the variety of colors in a deserted valley that looks like a scene from a science fiction movie.
Photo by Mark Rentz
Pukara de Quitor Archaeological Site
8.4/10 (42 reviews)
You can find out about the history of San Pedro de Atacama with a trip to Pukara de Quitor Archaeological Site. You can seek out the local tours in this quaint area.
Plaza de San Pedro de Atacama
8.4/10 (195 reviews)
You can find out about the history of San Pedro de Atacama with a trip to Plaza de San Pedro de Atacama. You can seek out the local tours in this quaint area.
Cerro Paranal Observatory
8.6/10 (4 reviews)
Commune with nature and explore the great outdoors at Cerro Paranal Observatory during your travels in Antofagasta. Amble around the area's seaside or visit its shops.
San Pedro Church
8.6/10 (64 reviews)
San Pedro Church is just one of the places to see in San Pedro de Atacama, so why not enjoy the other things to explore during your travels? You can seek out the local tours in this quaint area.
Piedra del Coyote Overlook
8.8/10 (61 reviews)
Explore the great outdoors at Piedra del Coyote Overlook, a lovely green space in San Pedro de Atacama. You can seek out the local tours in this quaint area.
Tulor Archaeological Site
8.4/10 (6 reviews)
You can find out about the history of San Pedro de Atacama with a stop at Tulor Archaeological Site. You can seek out the local tours in this quaint area.
Mall Plaza Calama
8.8/10 (9 reviews)
During your trip to Calama, you can enjoy retail therapy at Mall Plaza Calama. Discover the area's desert landscape and casinos.
What to do in Antofagasta Region
From San Pedro de Atacama: Geysers del Tatio Half-Day Tour
AU$79
per adult
80% of travellers recommend
San Pedro de Atacama: Stargazing Experience
AU$54
per adult
100% of travellers recommend
San Pedro de Atacama: Rainbow Valley Tour and Petroglyphs
AU$79
per adult
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
